Search results for " Aspiration"

showing 10 items of 72 documents

Current molecular and clinical insights into uveal melanoma (Review)

2021

Uveal melanoma (UM) represents the most prominent primary eye cancer in adults. With an incidence of approximately 5 cases per million individuals annually in the United States, UM could be considered a relatively rare cancer. The 90.95% of UM cases arise from the choroid. Diagnosis is based mainly on a clinical examination and ancillary tests, with ocular ultrasonography being of greatest value. Differential diagnosis can prove challenging in the case of indeterminate choroidal lesions and, sometimes, monitoring for documented growth may be the proper approach. Fine needle aspiration biopsy tends to be performed with a prognostic purpose, often in combination with radiotherapy. Gene expres…

0301 basic medicineOncologyUveal NeoplasmsCancer Researchmedicine.medical_specialtydiagnosisEnucleationBiology03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansNeoplasm MetastasisGrading (tumors)MelanomaBiomarkers; Diagnosis; Epigenetics; Prognosis; Staging; Treatment; Uveal melanomamedicine.diagnostic_testtreatmentepigeneticsMelanomaGene Expression ProfilingCancerbiomarkersArticlesstagingmedicine.diseasePrognosisPrimary tumor030104 developmental biologyFine-needle aspirationOncology030220 oncology & carcinogenesisMutationDifferential diagnosisuveal melanomaGNAQ
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Anaesthesia protocol evaluation of the videolaryngoscopy with the McGrath MAC and direct laryngoscopy for tracheal intubation in 1000 patients underg…

2021

IntroductionRapid sequence induction of anaesthesia is indicated in patients with an increased risk of pulmonary aspiration. The main objective of the technique is to reduce the critical time period between loss of airway protective reflexes and rapid inflation of the cuff of the endotracheal tube to minimise the chance of aspiration of gastric contents. The COVID-19 pandemic has reinforced the importance of first-pass intubation success to ensure patient and healthcare worker safety. The aim of this study is to compare the first-pass intubation success rate (FPS) using the videolaryngoscopy compared with conventional direct laryngoscopy in surgical patients with a high risk of pulmonary as…

1682medicine.medical_treatmenteducationLaryngoscopyLaryngoscopeslaw.inventionAnaesthesiasurgeryRandomized controlled triallawIntubation IntratrachealmedicineClinical endpointHumansMulticenter Studies as TopicIntubationAnesthesia1506adult anaesthesiaRapid Sequence Induction and Intubationadult intensive & critical carePandemicsRandomized Controlled Trials as TopicLaryngoscopymedicine.diagnostic_testSARS-CoV-2business.industryTracheal intubationCOVID-19General Medicinemedicine.diseaseRapid sequence inductionPulmonary aspirationAnesthesiaAirway managementbusinessBMJ Open
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Pulmonary actinomycosis. Fine needle aspiration diagnostic.

2011

Atículo publicado en: Invest Clin 52(4): 356 - 360, 2011 Se presentan 4 casos de actinomicosis pulmonar en pacientes mayores de 55 años, 2 de ellos con enfermedad pulmonar obstructiva crónica (EPOC), que mostraron un aumento de la tos productiva, episodios de disnea, hemoptisis y fiebre de larga evolución. En las radiografías de tórax de rutina se observaban imágenes segmentarias de consolidación aérea, sugestivas de cuadros neumónicos no resueltos o neoplasia. La tomografía axial computarizada (TAC) mostró hallazgos similares a los anteriores. Los cultivos de esputo y las pruebas de Mantoux fueron repetidamente negativos. Debido a la mala evolución de los pacientes y a los hallazgos radiol…

Actinomicosis pulmonarMedicina y SaludPulmónPunción-aspiración con aguja fina (PAAF)Fine needle aspiration (FNA)BiologíaPulmonary actinomycosisArtículosFacultad de Farmacia y BioanálisisLung
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Immunoperoxidase Staining of Fine-Needle Aspiration Biopsies of Renal Cell Carcinoma Using Tumor-Specific Monoclonal Antibody

1987

In 30 nephrectomy specimens, fine needle aspiration biopsies (FNAB) were performed both in the tumor and in the macroscopically normal part of the kidney: 18 were well differentiated renal cell carcinoma (RCC), 6 were moderately differentiated RCC, 4 were poorly differentiated RCC, and 2 were oncocytomas. FNAB was also performed in a bone metastasis of RCC. FNAB materials were stained using the immunoperoxidase method with RCC-specific monoclonal antibody and were compared with the staining of frozen sections. In all cases where tumor-antigen expression could be demonstrated in the frozen sections, a FNAB had already proven positive. There were only 2 false-negative cases where sufficient c…

AdenomaPathologymedicine.medical_specialtymedicine.drug_classUrologymedicine.medical_treatmenturologic and male genital diseasesMonoclonal antibodyImmunoenzyme TechniquesAntigens NeoplasmRenal cell carcinomaBiopsymedicineHumansCarcinoma Renal CellFrozen section proceduremedicine.diagnostic_testImmunoperoxidasebusiness.industryBiopsy NeedleAntibodies Monoclonalmedicine.diseaseKidney Neoplasmsfemale genital diseases and pregnancy complicationsNephrectomyStainingFine-needle aspirationbusinessEuropean Urology
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Determination of oestrogen receptors with monoclonal antibodies in fine needle aspirates of breast carcinoma.

1989

Fifty patients with operable breast carcinoma underwent fine needle aspiration for cytological examination. The smears were prepared by means of the immunocytochemical method using monoclonal antibodies for the determination of the oestrogen receptors (ER). After surgery the contents of the ER were determined with the traditional biochemical technique. The results of the immunocytochemical method showed 31 positives, two of which disagreed with the biochemical results, 15 negatives and four cases which could not be assessed due to the absence of adequate numbers of cells. The ICA staining for ER was expressed on a semiquantitative basis; there was a significant correlation between this and …

AdultCancer ResearchPathologymedicine.medical_specialtymedicine.drug_classBreast NeoplasmsBiologyMonoclonal antibodyBiopsyCarcinomamedicineHumansAgedmedicine.diagnostic_testEpitheliomaBiopsy NeedleAntibodies MonoclonalMiddle Agedmedicine.diseaseStainingFine-needle aspirationOncologyReceptors EstrogenMonoclonalFemaleBreast carcinomaResearch ArticleBritish journal of cancer
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Axillary Nodal Burden in Breast Cancer Patients With Pre-operative Fine Needle Aspiration-proven Positive Lymph Nodes Compared to Those With Positive…

2019

BACKGROUND/AIM: Recent years have seen a considerable shift to a more conservative management of the axilla in patients with positive axillary sentinel lymph nodes. The aim of this study was to determine whether some breast cancer patients with a preoperative ultrasound-guided needle aspiration biopsy proven positive node could potentially be spared an axillary lymph node dissection according to the ACOSOG Z0011 trial criteria. PATIENTS AND METHODS: A retrospective review was performed involving 623 breast cancer patients who underwent axillary lymph node dissection after either ultrasound-guided needle aspiration biopsy proven positive node or sentinel lymph node biopsy. RESULTS: Patients …

AdultCancer Researchmedicine.medical_specialtyaxillary nodal burdenCytodiagnosisSentinel lymph nodeBiopsy Fine-NeedleBreast NeoplasmsSensitivity and SpecificityGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineBreast cancerBreast cancerBiopsyPreoperative CareMedicineHumansBreastsentinel lymph node biopsyEndoscopic Ultrasound-Guided Fine Needle AspirationAgedRetrospective StudiesPharmacologyAged 80 and overmedicine.diagnostic_testbusiness.industryAxillary Lymph Node DissectionReproducibility of ResultsMiddle Agedmedicine.diseaseAxillaFine-needle aspirationmedicine.anatomical_structure030220 oncology & carcinogenesisLymphatic MetastasisAxillaFemaleRadiologyLymphLymph NodesbusinessNODALResearch Article
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Negative biopsy of focal hepatic lesions: Decision tree model for patient management

2019

OBJECTIVE. The purpose of this study was to investigate patient- and procedure-related variables affecting the false-negative rate of ultrasound (US)-guided liver biopsy and to develop a standardized patient-tailored predictive model for the management of negative biopsy results. MATERIALS AND METHODS. We retrospectively included 389 patients (mean age ± SD, 62 ± 12 years old) who had undergone US-guided liver biopsy of 405 liver lesions between January 1, 2013, and June 30, 2015. We collected multiple patient- and procedure-related variables. By comparing pathology reports of biopsy and the reference standard (further histology or imaging follow-up), we were able to categorize the biopsy r…

AdultImage-Guided BiopsyMalemedicine.medical_specialtyRadiology Nuclear Medicine and ImagingFalse Negative Result030218 nuclear medicine & medical imaging03 medical and health sciencesCore biopsyFalse-negative result0302 clinical medicineBiopsymedicineHumansFalse Negative ReactionsUltrasonography InterventionalAgedRetrospective StudiesAged 80 and overFine-needle aspirationmedicine.diagnostic_testUS-guided liver biopsybusiness.industryLiver DiseasesDecision TreesUltrasoundnutritional and metabolic diseasesGeneral MedicineMiddle AgedPatient managementDiagnostic errorFine-needle aspiration030220 oncology & carcinogenesisLiver biopsyFemaleRadiologybusinessCore biopsyDecision tree model
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Ultrasound-guided fine-needle aspiration cytology in the early detection of melanoma metastases.

2000

BACKGROUND. The early detection and treatment of tumor recurrences in melanoma patients is dependent on reliable, sensitive, and specific techniques to verify suspected tumor metastases. As of now, fine-needle aspiration cytology (FNAC) has yet to establish itself in the routine follow-up of melanoma patients. METHODS. FNAC procedures were performed in melanoma patients with palpable tumors or nonpalpable, ultrasonically suspicious lesions. Cytodiagnostic evaluation of fine-needle samples obtained from suspicious lesions was performed morphologically. Findings were validated either by histopathologic diagnosis or prolonged clinical follow-up. RESULTS. The cytologic examination of 739 FNACs …

AdultMaleCancer Researchmedicine.medical_specialtySkin NeoplasmsAdolescentEarly detectionSensitivity and SpecificityMetastasisFine needle aspiration cytologyCytologyBiopsymedicineHumansSampling (medicine)Neoplasm MetastasisMelanomaUltrasonography InterventionalAgedNeoplasm Stagingmedicine.diagnostic_testbusiness.industryMelanomaUltrasoundBiopsy NeedleReproducibility of ResultsMiddle Agedmedicine.diseasebody regionsOncologyFemaleRadiologybusinessCancer
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Fine-Needle Aspiration (FNAB) Molecular Analysis for the Diagnosis of Papillary Thyroid Carcinoma through BRAFv600E mutation and RET/PTC rearrangement

2007

Objective: To evaluate BRAFV600E mutation on consecutive fine-needle aspiration biopsy (FNAB) specimens in order to assess FNAB’s usefulness in preoperative papillary thyroid carcinoma (PTC) diagnosis with the contemporaneous analysis of RET=PTC1 and RET=PTC3 rearrangements obtained from ex vivo thyroid nodules. Design: Thyroid FNABs from 156 subjects with nodules and 49 corresponding surgical samples were examined for the presence of BRAF mutation by real-time allele-specific polymerase chain reaction, confirmed with the use of a laser pressure catapulting system. Samples were also examined for RET=PTC rearrangements. The results were compared with the cytological diagnosis and histopathol…

AdultMaleProto-Oncogene Proteins B-rafPathologymedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismBiopsyBiopsy Fine-NeedlePapillarySettore MED/08 - Anatomia PatologicaRET/PTCSettore MED/13 - EndocrinologiaThyroid carcinomaCohort StudiesEndocrinologyPredictive Value of TestsBiopsyCarcinomamedicine80 and overHumansThyroid NeoplasmsAgedRET/PTC RearrangementAged 80 and overGene Rearrangementmedicine.diagnostic_testbusiness.industryCarcinomaProto-Oncogene Proteins c-retGene rearrangementMiddle Agedmedicine.diseaseCarcinoma PapillaryAdult; Aged; 80 and over; Amino Acid Substitution; Biopsy; Fine-Needle; Carcinoma; Papillary; Cohort Studies; Female; Gene Rearrangement; Humans; Male; Middle Aged; Predictive Value of Tests; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-ret; Thyroid NeoplasmsBrafBRAF V600EFine-needle aspirationAmino Acid SubstitutionMutation (genetic algorithm)Fine-NeedleFemalebusiness
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From Educational Aspirations to Educational Attainment: The School Careers of the Children Of Immigrants in France and the United States

2008

08054

Educational Aspirations[SHS.EDU]Humanities and Social Sciences/EducationSchool Careers[SHS.EDU] Humanities and Social Sciences/EducationChildren of immigrants[ SHS.EDU ] Humanities and Social Sciences/EducationFranceEducational AttainmentUSA
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